Complement C3 and Autophagy Keep the β Cell Alive

Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive

Most neurological pathologies that afflict humans are associated with the abnormal accumulation and aggregation of specific proteins into the cytoplasm and with mitochondrial dysfunction. Neuronal health is sustained by the fine regulation of protein synthesis and organelle biogenesis and their degradation to ensure efficient turnover. Autophagy is a powerful process for removing such proteins ...

'....officiously to keep alive'.

Modern medical technology has provided powerful tools with which to initiate and sustain life and understandable concern is being expressed about scientists and doctors 'playing God.' The view that 'the clinician's freedom to stop intensive treatment when the probable outcome is severe handicap is part of the package of neonatology" is far from unanimous. The hard facts are, however, that today...

Why Keep Them Alive

How to keep photoreceptors alive.

O ver the last 40 years, there has been increasing success in the surgical treatment of retinal detachment in that the retinal reattachment could be achieved in a high proportion of cases but visual recovery was frequently poor. An explanation for this poor visual outcome was derived from work on experimental retinal detachment in which it was shown that photoreceptor cell death occurred becaus...

C3 and C4 Complement Levels in Iron Deficiency Anemia

Background and Objectives: Complement proteins are some of the most important plasma proteins of the innate immune system. Impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. This study was conducted to show whether serum C3 and C4 complement change in adult nonpregnant female with iron deficient anemia or ...